The first innovation specifically designed to prevent staining during antiseptic treatment in periodontal disease.
Nearly 70% of dentists consider spontaneous staining the main drawback of antiseptic use, leading to treatment discontinuation in 60% of cases.
The revolutionary formulation of VITIS Anti-stain prevents tooth staining and also cares for the gums during treatment phases.
Treatments with antiseptics such as chlorhexidine are a cornerstone of periodontal therapy. However, one of the most common side effects is tooth staining due to the interaction of these products with coffee, tea, wine or tobacco. These stains often hinder adherence, causing more than half of patients to discontinue treatment early, with negative consequences for their oral health.
To address this, scientists at the Dentaid Research Center —a leading European oral health research facility— have developed an innovative toothpaste that, for the first time, effectively prevents tooth staining without compromising the efficacy of antiseptics such as chlorhexidine.(1)
VITIS Anti-stain was created to meet the needs of both professionals and patients. Testing by the Dentaid Research Center shows up to 86%(2) stain prevention when combined with chlorhexidine and various ingredients. Beyond stain control, the challenge was to ensure optimal gum care, as tissues are more delicate during periodontal treatment.
Two key elements of the formulation
The new formula features a dual phosphate system that forms a protective layer on enamel while inhibiting plaque formation by preventing the adhesion of staining molecules. It also contains polyvinylpyrrolidone (PVP), which prevents staining by binding to and dissolving chromogens found in the diet (coffee, tea or tobacco).
“We understand that patients undergoing treatment have delicate oral tissues, and we have developed a formula that takes their specific needs into account and is effective against staining.”
Sandra Bosch, researcher at the Dentaid Research Center.
This innovation is gentle on delicate gums during treatment. In addition, VITIS Anti-stain contains 1450 ppm fluoride to protect against caries and strengthen enamel, making it suitable for daily use.
Positive impact on clinical practice
Adherence to antiseptic treatment is a common challenge in daily practice. Recent studies show that up to 60% of patients discontinue treatment due to aesthetic concerns such as tooth staining.1 This solution provides practitioners with a tool to enhance the patient experience, encourage treatment continuity and optimise therapeutic outcomes.
“As a professional, it is essential to explain to patients why we are prescribing chlorhexidine to help them understand the importance of completing the treatment and preventing infections. We can also prescribe a solution or product to prevent the treatment’s side effects.”
Dr Rui Figueiredo, coordinator of the Master's in Oral Surgery and Buccofacial Implantology (University of Barcelona) and Vice President of SECIB.
An increasing number of professionals recognise the impact of staining on adherence and seek effective solutions to enhance their patients’ experience. VITIS Anti-stain is now a key complement for antiseptic treatments.
- Hamilton Global Intelligence Study for Dentaid. April 2024.
2. Gómez R, Àlvarez G, Bosch S, Longo A, Massoli A, Blanc V. In vitro evaluation of a new toothpaste formulation for the prevention and removal of stains caused by the use of antiseptics. Oral communication presented at: 22nd International Congress of the Italian Society of Periodontology and Implantology (SIdP); 2025 Mar 13–15; Rimini, Italy.
Treatments with antiseptics such as chlorhexidine are a cornerstone of periodontal therapy. However, one of the most common side effects is tooth staining due to the interaction of these products with coffee, tea, wine or tobacco. These stains often hinder adherence, causing more than half of patients to discontinue treatment early, with negative consequences for their oral health.
To address this, scientists at the Dentaid Research Center —a leading European oral health research facility— have developed an innovative toothpaste that, for the first time, effectively prevents tooth staining without compromising the efficacy of antiseptics such as chlorhexidine.(1)
VITIS Anti-stain was created to meet the needs of both professionals and patients. Testing by the Dentaid Research Center shows up to 86%(2) stain prevention when combined with chlorhexidine and various ingredients. Beyond stain control, the challenge was to ensure optimal gum care, as tissues are more delicate during periodontal treatment.
Two key elements of the formulation
The new formula features a dual phosphate system that forms a protective layer on enamel while inhibiting plaque formation by preventing the adhesion of staining molecules. It also contains polyvinylpyrrolidone (PVP), which prevents staining by binding to and dissolving chromogens found in the diet (coffee, tea or tobacco).
“We understand that patients undergoing treatment have delicate oral tissues, and we have developed a formula that takes their specific needs into account and is effective against staining.”
Sandra Bosch, researcher at the Dentaid Research Center.
This innovation is gentle on delicate gums during treatment. In addition, VITIS Anti-stain contains 1450 ppm fluoride to protect against caries and strengthen enamel, making it suitable for daily use.
Positive impact on clinical practice
Adherence to antiseptic treatment is a common challenge in daily practice. Recent studies show that up to 60% of patients discontinue treatment due to aesthetic concerns such as tooth staining.1 This solution provides practitioners with a tool to enhance the patient experience, encourage treatment continuity and optimise therapeutic outcomes.
“As a professional, it is essential to explain to patients why we are prescribing chlorhexidine to help them understand the importance of completing the treatment and preventing infections. We can also prescribe a solution or product to prevent the treatment’s side effects.”
Dr Rui Figueiredo, coordinator of the Master's in Oral Surgery and Buccofacial Implantology (University of Barcelona) and Vice President of SECIB.
An increasing number of professionals recognise the impact of staining on adherence and seek effective solutions to enhance their patients’ experience. VITIS Anti-stain is now a key complement for antiseptic treatments.
- Hamilton Global Intelligence Study for Dentaid. April 2024.
2. Gómez R, Àlvarez G, Bosch S, Longo A, Massoli A, Blanc V. In vitro evaluation of a new toothpaste formulation for the prevention and removal of stains caused by the use of antiseptics. Oral communication presented at: 22nd International Congress of the Italian Society of Periodontology and Implantology (SIdP); 2025 Mar 13–15; Rimini, Italy.
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